Emergency crews responded to the scene just before 2 p.m. where a Chevrolet Tahoe and Chrysler PT crashed in the intersection of Corral Hollow and West Larch roads.
The impact caused the Tahoe to roll onto its roof and sent the PT Cruiser sliding into the northbound lanes.
Tracy Fire crews worked to stop fuel leaking from the overturned Tahoe.
Traffic was diverted off Corral Hollow Road and to Larch Road.
Two victims were taken with minor injuries to Sutter Tracy Hospital.
California Highway Patrol is investigating the crash, and as of 4 p.m. Friday, August 10, no further information was available.